Preheat oven to 400°F (200°C). Line a baking sheet with parchment paper.
In a shallow dish, combine the Parmesan cheese, panko breadcrumbs, garlic powder, onion powder, Italian seasoning, salt, and pepper. Mix well.
In a second shallow dish, whisk the eggs.
In a third shallow dish, place the flour.
Pat the chicken breasts dry with paper towels. If the chicken breasts are very thick, pound them to an even thickness for quicker and more even cooking.
Dredge each chicken breast first in the flour, shaking off any excess. Then dip it into the whisked eggs, letting any excess drip off. Finally, coat both sides generously with the Parmesan-breadcrumb mixture, pressing gently to adhere.
Heat the olive oil in a large oven-safe skillet over medium-high heat. Sear the chicken for 2-3 minutes per side, until lightly golden.
Transfer the skillet to the preheated oven (or place the seared chicken on the prepared baking sheet). Bake for 15-20 minutes, or until the chicken is cooked through and the internal temperature reaches 165°F (74°C).
Let rest for a few minutes before serving.
Notes
Serve with your favorite side dishes like pasta, salad, or roasted vegetables.